Background: Jatamansi/Nardostachys jatamansi (NJ) is an important aromatic shrub widely used by Ayurvedic practitioners for centuries due to its usefulness in intellect-enhancing (Medhya), strengthening (Balya), and skin disorders.Several classical dosage forms like hot or cold infusion, decoction, distillate, powders, etc.have been mentioned for NJ.
Clinical trials of Jatamansi Oil (JO) as a head massage click here conducted by clinicians and therapists have shown encouraging results in de-stressing/stress management of cancer patients through head anointing treatment.Objective: Such effective proprietary formulation needs assessment of its characteristics using modern analytical technologies to comprehend the Ayurvedic concept of dermal pharmacology.Materials and methods: Triplicate batches of JO were prepared by evaporating its decoction in sesame oil (SO).
Basic physicochemical analysis of the raw material, in-process samples, and finished products was carried out to develop a monograph.Further, raw SO and finished product JO were subjected to TLC, and extracted in hexane and dichloromethane separately for Gas Chromatography-Mass Spectrometry (GC-MS) analysis to profile several bioactive molecules silver lining herbs kidney support from NJ in the final product, JO.Results: Standard Operating Procedure was developed and a basic monograph was prepared for JO.
GC-MS analysis revealed several phytocompounds dissolved/dispersed in SO after processing, while 18 additional distinct peaks were observed in JO as compared to SO.Conclusion: This preliminary analysis supports the Ayurvedic concept of lipid-based formulations.The plausible phytocompounds anticipated based on retention times can be further quantified and studied for their probable action as anointing treatment.
A detailed experimental strategy for understanding the phytochemical changes during the entire process needs to be planned and performed.